Academic Staff

Dr. Chan

Dr. Cheng Pak Wing, Calvin 鄭柏榮

MBBS (HKU), FHKAM(Psychiatry), FHKCPsych
MA in Philosophy (CUHK)
Master of Buddhist Studies (HKU)

Clinical Assistant Professor
Honorary Associate Consultant, Queen Mary Hospital
Associate Editor-in-chief, East Asian Archives of Psychiatry
Representative of Hong Kong West Cluster, Clinical Division of Old Age Psychiatry, The Hong Kong College of Psychiatrists

Email: chengpsy@hku.hk
The HKU Scholars Hub Page address:https://hub.hku.hk/cris/rp/rp02337





Biography:

Dr. Calvin Cheng joined the department in November 2017 as a clinical assistant professor. He is also the honorary associate consultant of psychogeriatric services in the Hong Kong West Cluster. Before joining the department, he obtained Fellowship of the Hong Kong College of Psychiatrists in 2014. He was the visiting fellow and trained as a functional MRI specialist under Athinoula A. Martinos Center for Biomedical Imaging in the Massachusetts General Hospital in same year. He also attended intensive courses of transcranial magnetic and electrical stimulation in Harvard Medical School, Universitätsmedizin Göttingen and University Medical Center Utrecht from 2014 to 2016. His current research interests reside in pharmacological and non-pharmacological interventions for geriatric depression, structural and functional brain mapping, non-invasive transcranial brain stimulation for mood disorder and cognitive impairment in elderly. He obtained Distinguished Young Fellow Award given by the Hong Kong Academy of Medicine in 2018.

Research Interests

  • Late-life depression and Late-life psychosis
  • Mild cognitive impairment, dementia or neurocognitive disorder
  • Dementia care-giver
  • Non-invasive brain stimulation, such as Transcranial magnetic stimulation (TMS) and Direct current stimulation (tDCS)
  • Neuroimaging
  • Service/intervention evaluation

Current research projects

  1. High-definition transcranial direct current stimulation (HD-tDCS) as augmentation therapy in late-life depression (LLD) with suboptimal response to treatment - double-blinded randomized sham-controlled trial
    (HMRF – Full grant, 17181141, PI)
  2. Inflammation hypothesis for late-life depression (LLD): How the brain connectivity mediates the effect of inflammation on LLD symptoms
  3. Does telomere length mediate the cognitive impairment in late-life depression (LLD)
    (Seed Fund for Basic Research, 201811159104, PI)
  4. Parent Education in Mental Health – Primary School (PEMH) – Service evaluation project
  5. Efficacy and safety of transcranial pulse stimulation (TPS) in older adults with mild neurocognitive disorder– an open-label self-controlled trial
    (Seed Fund for Basic Research, 201910159063, PI)
  6. The Hong Kong Mental Morbidity Survey for Older Persons
    (HMRF commissioned study, FHB/G/41/155, Co-I)
  7. Tai chi versus conventional exercise to alleviate depressive symptoms in older insomniacs: a comparative efficacy randomized controlled trial
    (HMRF – Full grant,17182461, Co-I)

Selected Publication List

1. Louie Larissa Lok Chi., Chan Wai Chi., & Cheng Pak Wing, Calvin. Suicidal risk in elderly patients with depression during Coronavirus Disease 2019 epidemic: A Case Control Study. East Asian Archives of Psychiatry. (Accepted)
2. Cheng, P. W. C., Louie, L. L. C., Wong, Y. L., Wong, S. M. C., Leung, W. Y., Nitsche, M. A., & Chan, W. C. (2020). The effects of transcranial direct current stimulation (tDCS) on clinical symptoms in schizophrenia: A systematic review and meta-analysis. Asian Journal of Psychiatry, 53, 102392.
3. Cheng, P. W. C., Chang, W. C., Lo, G. G., Chan, K. W. S., Lee, H. M. E., Hui, L. M. C., ... & Mak, K. F. H. (2020). The role of dopamine dysregulation and evidence for the transdiagnostic nature of elevated dopamine synthesis in psychosis: a positron emission tomography (PET) study comparing schizophrenia, delusional disorder, and other psychotic disorders. Neuropsychopharmacology, 0:1–7; https://doi.org/10.1038/s41386-020-0740-x
4. Cheng, C. P. (2020). New 21st Century Intervention in Psychiatry – Non-invasive Brain Stimulation (NIBS): Potential and Future Development. The Hong Kong Medical Diary, 25(3), 12-14.
5. Wong, H. L., Chan, W. C., Wong, Y. L., Wong, S. N., Yung, H. Y., Wong, S. M. C., & Cheng, P. W. C. (2019). High‐definition transcranial direct current stimulation—An open‐label pilot intervention in alleviating depressive symptoms and cognitive deficits in late‐life depression. CNS neuroscience & therapeutics, 25(11), 1244-1253.
6. Hanna Lu, Sandra Sau Man Chan, Wai Chi Chan, Cuichan Lin, Calvin Pak Wing Cheng & Lam Linda Chiu Wa (2019). Randomised Controlled Trial of TDCS on Cognition in 201 Seniors with Mild Neurocognitive Disorder. Annals of Clinical and Translational Neurology. DOI:10.1002/acn3.50823
7. Cheng, C. P. W. & Chan W.C. (2019). Benzodiazepines, Encyclopedia of Gerontology and Population Aging, Danan Gu, Matthew E. Dupre, Springer International Publishing, 1-3
8. Cheng, C. P. (2018). Elderly care as one of the important government policy agenda. Hong Kong Med J, 24, 442-3.
9. Cheng, C. P. W., Cheng, S. T., Tam, C. W. C., Chan, W. C., Chu, W. C. W., & Lam, L. C. W. (2018). Relationship between Cortical Thickness and Neuropsychological Performance in Normal Older Adults and Those with Mild Cognitive Impairment. Aging and Disease, 9(6), 1020.
10. Cheng, C. P. W., Wong, C. S. M., Lee, K. K., Chan, A. P. K., Yeung, J. W. F., & Chan, W. C. (2018). Effects of repetitive transcranial magnetic stimulation on improvement of cognition in elderly patients with cognitive impairment: a systematic review and meta‐analysis. International journal of geriatric psychiatry, 33(1), e1-e13.
11. Cheng, C. P. W., Chiu-Wa Lam, L., & Cheng, S. T. (2016). The Effects of Integrated Attention Training for Older Chinese Adults With Subjective Cognitive Complaints: A Randomized Controlled Study. Journal of Applied Gerontology, 0733464816684622.
12. Cheng, C. P., Chan, S. S., Mak, A. D., Chan, W. C., Cheng, S. T., Shi, L., ... & Lam, L. C. W. (2015). Would transcranial direct current stimulation (tDCS) enhance the effects of working memory training in older adults with mild neurocognitive disorder due to Alzheimer’s disease: study protocol for a randomized controlled trial. Trials, 16(1), 479.