Academic Staff

Dr. Lui

Dr. LUI Sai Yu, Simon 呂世裕

MBBS, PhD, FRCPsych(UK), FHKCPsych, FHKAM(Psychiatry)

Clinical Associate Professor, Department of Psychiatry, HKU

The HKU Scholars Hub Page address: ORCID: 0000-0001-9360-6244


Dr. Simon Lui joined the Department of Psychiatry in 2020. He is currently a Clinical Associate Professor. He is a medical graduate from the HKU, and completed his specialist training in Castle Peak Hospital (CPH). Before joining the department, he was an Associate Consultant (2011-2020) in CPH, and has accumulated rich clinical and administrative experiences, and has worked in various psychiatric subspecialties. He is a fellow of the Royal College of Psychiatrists (UK), and specialized in early psychosis. Working in a research-clinical team in the Hospital Authority, he had conducted many studies on psychosis, and obtained a doctoral degree in cognitive neurosciences (2013). As a clinician-scientist, he has published around 90 journal articles (as of Oct 2020).

Research Interests:

  • Neurobiological basis of psychosis
  • Cognitive markers and endophenotype research
  • Clinical studies in early psychosis intervention
  • Behavioral-high-risk populations for psychosis


Selected Research Publications:


Lui, S.S.Y., Hung, K.S.Y., Wang, Y., Ho, K.K.Y., Yeung, H.K.H., Wang, Y., Huang, H., Gooding, D.C., Cheung, E.F.C.,& Chan, R.C.K. (2018). Clustering of schizotypy features in unaffected first-degree relatives of schizophrenia patients. Schizophrenia Bulletin doi:10.1093/schbul/sby035.


Xie, D.J., Lui, S.S.Y., Geng, F.L., Yang, Z.Y., Zou, Y.M., Li, Y., Yeung, H.K.H., Cheung, E.F.C., Heerey, E.A.,& Chan, R.C.K. (2017). Dissociation between affective experience and motivated behaviour in schizophrenia patients and their unaffected first-degree relatives and schizotypal individuals. Psychological Medicine doi: 10.1017/S0033291717002926.

3. Tin, L.N.W., Lui, S.S.Y., Ho, K.K.Y., Hung, K.S.Y., Wang, Y., Yeung, H.K.H., Wong, T.Y., Lam, S.M., Chan, R.C.K.,& Cheung, E.F.C. (2017). High-functioning autism patients share similar but more severe impairments in verbal theory of mind than schizophrenia patients. Psychological Medicine doi: 10.1017/S0033291717002690.
4. Lui, S.S.Y., Yang, T.X., Ng, L.Y., Wong, P.T.Y., Wong, J.O.Y, Ettinger, U., Cheung, E.F.C.,& Chan, R.C.K. (2017). Following instructions in patients with schizophrenia: The benefit of actions at encoding and recall. Schizophrenia Bulletin 44: 137–146.
5. Lui, S.S.Y., Liu, A.C.Y., Chui, W.W.H., Li, Z., Geng, F.L., Wang, Y., Heerey, E.A., Cheung, E.F.C., Chan, R.C.K. (2016). The nature of anhedonia and avolition in patients with first-episode schizophrenia. Psychological Medicine 46(2), 437-447.
6. Ho, K.K.Y., Lui, S.S.Y., Hung, K.S.Y., Wang, Y., Li, Z., Cheung, E.F.C.,& Chan, R.C.K (2015). Theory of mind impairments in patients with first-episode schizophrenia and their unaffected siblings. Schizophrenia Research 166, 1–8.

Lui, S.S.Y., Wang, Y., Yang, T.X., Liu, A.C.Y., Chui, W.W.H., Yeung, H.K.H., Li, Z., Neumann, D.L, Shum, D.H.K., Cheung, E.F.C.,& Chan, R.C.K. (2015). Problems in remembering to carry out future actions in first-episode schizophrenia: primary or secondary impairment? Journal of Psychiatric Research 61, 141-149.

8. Lui, S.S.Y., Sham, P.C., Chan, R.C.K.,& Cheung, E.F.C. (2011). A family study of endophenotypes for psychosis within an early intervention programme in Hong Kong: Rationale and preliminary findings. Chinese Science Bulletin 56(32), 3394-3397.
9. Lui, S.S.Y., Wang, Y., Liu, A.C.Y., Chui, W.W.H., Gong, Q.Y., Shum, D.H.K., Cheung, E.F.C.,& Chan, R.C.K. (2011). Prospective memory in patients with first-onset schizophrenia and their non-psychotic siblings. Neuropsychologia 49(8), 2217-24.