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Re-orientation of neurological soft signs: Implications for precision psychiatry for psychosis

Departmental Research Grand Round

Presented by: 

Professor Chan Choi Kiu Raymond (Distinguished Professor of Neuropsychology and Applied Cognitive Neuroscience, the Institute of Psychology of the Chinese Academy of Sciences)

Chaired by:

Professor SHAM Pak Chung (Chair Professor in Psychiatric Genetics)


5 October 2023


9:00 am


10:00 am


Lecture Room 211 A&B, 2/F, New Clinical Building, Queen Mary Hospital and Zoom


Increasing efforts to identify alternate expressions of mental disorders that are broader than the DSM

or ICD diagnostic criteria reflects a growing consensus that multidimensional expressions of psychiatric

disorders may advance the search for underlying etiological or modulatory factors. These alternate

phenotypes or ‘endophenotypes’ of disorders may be more specific and amenable to objective

measurement than clinical symptoms, which presumably reflects variation among smaller numbers of

genes than more distal clinical symptoms. This presentation aims to address several unresolved issues

of a promising endophenotype, neurological soft signs (NSS), including the debate of specificity of NSS

across the different diagnostic groups of neuropsychiatric disorders, the brain structural and functional

connectivity association with NSS in schizophrenia. These findings also highlight the reo-orientated

important roles of NSS in schizophrenia research and implicate for precision psychiatry for psychosis.


Please click into the below link for registration (face-to-face or zoom) as follows:


Deadline for registration is 5 October 2023.

Zoom link of the seminar will be automatically sent to registered email address after registration.

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