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The roles of genetic and environmental factors in treatment resistant schizophrenia: a whole genome sequencing project

Research-in-progress Seminar

Presented by: 

Mr LEUNG Bok Man Perry (PhD candidate)

Chaired by:

Dr LEE Chi Kei Krystal (Clinical Assistant Professor)


24 August 2023


8:00 am


9:00 am


J2 Seminar Room, Block J, QMH (face-toface


Schizophrenia is a highly heterogeneous mental disorder with complex aetiology, and between one fifth

to one third of patients would develop “treatment-resistant” schizophrenia (TRS). My PhD project,

based on genome analysis, aims to address the following research questions: 1) Whether TRS and

treatment responsive schizophrenia are distinct genetic subtypes; 2) Whether gene-environment

interactions (G × E) can be used to identify clinically high-risk groups who could develop schizophrenia

and/or TRS.

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