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The roles of genetic and environmental factors in treatment resistant schizophrenia: a whole genome sequencing project
Research-in-progress Seminar
Presented by:
Mr LEUNG Bok Man Perry (PhD candidate)
Chaired by:
Dr LEE Chi Kei Krystal (Clinical Assistant Professor)
Date:
24 August 2023
Time:
8:00 am
-
9:00 am
Venue:
J2 Seminar Room, Block J, QMH (face-toface
Abstract:
Schizophrenia is a highly heterogeneous mental disorder with complex aetiology, and between one fifth
to one third of patients would develop “treatment-resistant” schizophrenia (TRS). My PhD project,
based on genome analysis, aims to address the following research questions: 1) Whether TRS and
treatment responsive schizophrenia are distinct genetic subtypes; 2) Whether gene-environment
interactions (G × E) can be used to identify clinically high-risk groups who could develop schizophrenia
and/or TRS.
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