Polygenicity of complex traits: a decade's journey of GWAS discovery and statistical modelling
Mr. CHEN Guolan, Lane
Dr. CHENG Pak Wing, Calvin
28 July 2022
Hybrid (Faceto- face and Zoom)
Ever since the milestone GWAS studies of SCZ and BD published in 2009, geneticists have progressed to
realize that most complex traits, including common diseases, are polygenic with numerous contributive
loci, and the genome-wide cumulative burden of risk alleles determines individual risk in conjunction
with environmental factors. This profound perception is greatly attributed to advancement of
sophisticated statistical modelling, which not only helped to solve the mystery of "missing heritability",
but also becomes the key to quantifying trait polygenicity and individual polygenic risk.
Registration Link: Please click into the below link for registration (face-to-face or zoom)as follow:
Deadline for registration is 28 July 2022 at 12:00 noon.
Zoom link of the seminar will be automatically sent to registered email address after registration.