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Polygenicity of complex traits: a decade's journey of GWAS discovery and statistical modelling

Presented by:

Mr. CHEN Guolan, Lane

Chaired by:

Dr. CHENG Pak Wing, Calvin


28 July 2022


7:05 am


7:40 am


Hybrid (Faceto- face and Zoom)


Ever since the milestone GWAS studies of SCZ and BD published in 2009, geneticists have progressed to

realize that most complex traits, including common diseases, are polygenic with numerous contributive

loci, and the genome-wide cumulative burden of risk alleles determines individual risk in conjunction

with environmental factors. This profound perception is greatly attributed to advancement of

sophisticated statistical modelling, which not only helped to solve the mystery of "missing heritability",

but also becomes the key to quantifying trait polygenicity and individual polygenic risk.


Registration Link: Please click into the below link for registration (face-to-face or zoom)as follow:


Deadline for registration is 28 July 2022 at 12:00 noon.

Zoom link of the seminar will be automatically sent to registered email address after registration.

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